Steroid Injection for Knee Pain and Knee Joint Osteoarthritis
Osteoarthritis (OA)—often called ‘wear-and-tear’ or ‘degenerative joint disease’ – is an arthritic condition in which the surfaces within your joints become damaged, so the joint doesn’t move as smoothly as it should. As the cartilage degenerates, the space between the joint narrows and the bones begin grinding against each other, leading to increased pain and reduced function.
Osteophytes (bony spurs) may form, creating more friction in the joint and further contributing to arthritic pain.
A knee steroid injection is a common procedure used to help manage the pain and inflammation caused by knee osteoarthritis. It involves injecting a corticosteroid medication directly into the joint to reduce inflammation and improve movement.
In the UK, patients can access knee steroid injection therapy through the NHS or private clinics. Choosing private treatment can offer faster access and personalized care, but it’s important to discuss the cost in advance, as prices can vary depending on the clinic and the specific procedure offered.

Katie’s Journey with Knee Steroid Injection Therapy and Knee Osteoarthritis
Katie has managed knee osteoarthritis for 20 years. She manages her condition with a combination of exercise, mobility, medication and steroid injections in to the knee. At 90 years old, she is able to share her wisdom in this video about what she finds is most useful and how she feels when she has a steroid injection in her knees. If you have pain from osteoarthritis and are considering if a steroid injection in the knee is right for you, then this video will show you the process and give insight from one of our actual patients.Causes
As part of normal life, your joints are exposed to a constant low level of damage. In most cases, your body repairs itself and you do not experience any symptoms. Almost everyone will eventually develop some degree of osteoarthritis. One common myth is that exercise like running will “wear out your knees”. In actual fact, research shows that people who run recreationally are less likely to develop arthritis in the knee than someone who is mostly sedentary (Alentorn-Geli et al, 2017).
However, several factors increase the risk of developing significant arthritis.
Risk factors include:
- Age. Osteoarthritis usually starts from the late 40s onwards (Blagojevic et al, 2010). This could be due to the weakening of the muscles, the body being less able to heal itself and the gradual wearing out of the joint with time. A study found that 33% of individuals older than 75 years have symptomatic and radiographic signs of knee osteoarthritis (Katz et al, 2021).
- Obesity. Weight increases the pressure in all the joints and greatly increases your risk of developing osteoarthritis (Katz et al, 2021). One pound of body weight results in 4 pounds of pressure on the knee joint (Messier et al, 2006).
- Gender. Osteoarthritis in the knee is twice as likely in women than men. (Blagojevic et al, 2010).
- Genetics. Studies have found that those with a family history of knee osteoarthritis have an increased risk of developing osteoarthritis (Katz et al, 2021).
- Joint Injury. Injuries to the knee such as a torn meniscus or ligament injury can increase the risk of developing knee osteoarthritis in later life (Katz et al, 2021).
- Muscle weakness and joint laxity has been found to increase risk of symptomatic knee osteoarthritis (Zhang et al, 2010). A recent review found that knee extensor weakness increases risk of symptomatic knee osteoarthritis in men and women (Oiestead, B.E et al, 2021).
- Sedentary lifestyle has been found to be a risk for developing osteoarthritis (Katz et al, 2021). Those with knee osteoarthritis spent two-thirds of their daily time in sedentary behaviour (Lee at al, 2015).
Symptoms of Knee Joint Osteoarthritis
- Pain. Often described as a deep dull ache that is hard to locate. It tends to affect walking, kneeling, and certain exercises. In more severe cases, people may discuss options like having a knee steroid injection to help reduce inflammation and manage persistent pain.
- Stiffness. You may feel stiffness in the knee at certain times, often in the morning or after a period of rest. A knee steroid injection may be considered when stiffness is due to inflammation that doesn’t respond to simpler measures.Stiffness. You may feel stiffness in the knee at certain times, often in the morning or after a period of rest. A knee steroid injection may be considered when stiffness is due to inflammation that doesn’t respond to simpler measures.
- Creaking or grinding sensation when the joint moves.
- Swelling. You may notice hard swelling (caused by osteophytes) or soft swelling (caused by extra fluid in the joint). A knee steroid injection can help reduce joint swelling by targeting inflammation directly.
Anatomy
The knee is made up of two joints, the tibiofemoral joint and the patellofemoral joint. The tibiofemoral joint is a hinge joint formed by the tibia (shin bone) and femur (thigh bone). The patellofemoral joint is formed between the femur (thigh bone) and the patella (kneecap). The ends of the bones are covered with articular cartilage, which acts as a protective coating and produces lubrication for smooth movement.The tibiofemoral joint is the weight-bearing component of the knee. On top of the tibia are two semi-circular cartilage structures called the menisci. The menisci provide shock absorption, improve congruency, and reduce friction during flexion and extension of the knee.The patellofemoral joint acts as a pulley for the quadriceps muscle, enabling more efficient knee extension and increased quadriceps power. For patients struggling with persistent inflammation despite conservative care, a steroid injection into the knee can be an option to help relieve symptoms and improve function.
How to diagnose
One of our highly skilled physiotherapists will ask a series of questions and perform a physical examination to help develop a diagnosis.An X-RAY can be used to assess the stage of arthritis – if it is mild, moderate or severe. It is important to note that the severity of arthritis found on the XRAY does not always correlate to the level of pain.
Treatment
A knee replacement is not the only option when treating knee osteoarthritis.
Osteoarthritis of the knee joint can be well managed with conservative treatment and not require surgical intervention. Although it is not possible to reverse the degenerative changes, it is possible to reduce pain, improve strength and function.
Physiotherapy
The muscles surrounding your knee joint are like scaffolding. Strengthening the muscles around your knee can help stabilise and protect the joint. It’s also been shown to reduce pain and will prevent your knee giving way and therefore reducing the tendency to fall (Hunter et al 2009).
Aerobic exercise can reduce pain by stimulating the release of pain-relieving hormones called endorphins (Tanaka et al, 2013). It can also help you sleep easier, which is important for general health and well-being.
Our physiotherapists can advise on the best exercises to help build strength and fitness, whilst addressing each individual’s needs. It is important to have the right balance between rest and exercise, as too much activity can increase pain, whilst too little can cause the joints to stiffen up and deteriorate further.
Weight Management
Being overweight increases your risk of developing osteoarthritis and also makes it more likely the arthritis will get worse over time. When you walk, run or go up and down stairs the knee can take up to three to six times your body weight (Costigan et al, 2002). Therefore, even losing a small amount of weight can have a big difference to the strain on your knees. If you need to lose weight, you should follow a balanced, reduced-calorie diet combined with regular exercise.
Other ways you can help manage your pain
- Pace activities.
- Wear low-heeled shoes with soft, thick soles (such as trainers).
- Avoid keeping your knee still in a bent position for too long.
- Speak to your pharmacist about taking over the counter pain relief such as paracetamol or ibuprofen
Knee Osteoarthritis Injection Therapy
If symptoms do not improve with conservative treatment, or if the pain is affecting your sleep, stopping you from everyday activities such as walking, or limiting your physiotherapy exercises, injection therapy may be a beneficial procedure for you. In the UK, both NHS and private clinics offer this option, though the cost can vary depending on the setting and specific injection type.Knee Steroid Injection therapy has been proven effective for reducing arthritic joint pain. Current evidence shows that injections performed under ultrasound guidance are more accurate and more effective at reducing pain and improving function than landmark-guided injections (Daniels et al., 2018).Ultrasound-Guided Knee Steroid Injection A knee steroid injection uses a small dose of corticosteroid (a strong anti-inflammatory drug) injected under ultrasound guidance directly into the joint. This procedure is designed to reduce pain and inflammation caused by arthritic changes in the knee. It improves function, allows better exercise tolerance, and may help delay the need for surgery. In the UK, private clinics like ours often provide fast access to ultrasound-guided injections, with the cost depending on the treatment and specialist.Ultrasound-Guided Hyaluronic Acid Injection Hyaluronic acid (HA) is a naturally occurring, gel-like substance that lubricates the joints to reduce friction. This procedure involves injecting HA into the knee joint to improve lubrication, absorb shock, and reduce pain and inflammation from arthritic wear and tear. Many private UK clinics offer this service, and patients are advised to discuss the expected cost and benefits in advance.Arthrosamid Injection Arthrosamid is a newer injectable treatment for arthritic knee conditions. This procedure involves a single injection that integrates into the joint lining and does not break down like steroids or hyaluronic acid. It may provide the most long-lasting symptom relief among injection options if appropriate for you. Private clinics in the UK typically offer Arthrosamid, with cost varying based on the provider.Ultrasound-Guided Platelet Rich Plasma (PRP) Injection PRP has become increasingly popular in managing arthritic knee pain. This procedure involves drawing a small amount of your blood, using a centrifuge to separate its components, and extracting plasma rich in platelets and growth factors that aid tissue regeneration. The plasma is then injected into the knee joint under ultrasound guidance. Many people choose PRP because it uses the body’s own cells without drugs. In the UK, private clinics typically offer PRP injections with varying cost based on the provider and package.Other Knee Conditions:
References
Alenton-Geli, E., Samuelsson, K., Musahl, V., Green, C.L., Bhandari, M. and Karlsson, J. (2017) The association of recreational and competitive running with hip and knee osteoarthritis: a systematic review and meta-analysis.Journal of Orthopaedic and Sports Physical Therapy. 47(6). Pp.373-390.
Blagojevic, M., Jinks, C., Jeffery, A. and Jordan. K.P. (2009) Risk factor for onset of osteoarthritis of the knee in older adults: a systematic review and meta-analysis. Osteoarthritis Cartilage. 18(1) pp.24-33.
Daniels, E.W., Cole, D., Jacobs, B. and Phillips, S.F., 2018. Existing Evidence on Ultrasound-Guided Injections in Sports Medicine. Los Angeles, CA: SAGE Publications.
Hunter, D.J. and Bierma-Zeinstra,S. (2019) Osteoarthritis. The Lancet. 39 (10182). pp.1745-1759.
Katz, J.N., Arant, K.R. and Loeser, R.F. (2021. Diagnosis and Treatment of Hip and Knee Osteoarthritis: A review. Journal of the American Medical Association. 325 (6). pp.568-578.
Kim, C., Linsenmeyer KD., Vlad, S.C, Guermaxi, A., Clancy, M., Niu, J. and Felson, D.T. (2014) Prevalence of radiographic and symptomatic hip osteoarthritis in an urbal United States community: the Framingham osteoarthritis study. Arthritis Rheumatology. 66(11). pp . 3013-3017.
Lee, J., Rowland, W.C., Ehrlich-Jones, L., Kwoh, C.K., Nevitt, M., Semanik, P.A., Sharma, L., Sohn, M-W. Song, J. and Dunlop, D.D. (2015) Sedentary behaviour and physical function: objective evidence from Osteoarthritis Initiative. Arthritis care and research. 67(3) . pp. 366-373.
Messier, S.P., Gutekunst, D.J., David, C. and De Vita, P. (2005) Weight loss reduces knee-joint loads in overweight and obese older adults with knee osteoarthritis. Arthritis and Rheumatism. 52(7) pp. 2026-2032.
Oiestad, B.E., Juhl, C., Culvenor, A.G., Berg, B. and Thorlund, J.B. (2021) Knee extensor muscle weakness is a risk factor for the development of knee osteoarthritis: an updated systematic review and meta-analysis including 46,819 men and women. British journal of sports medicine. 56(1). pp .349-355.
Tanaka, R., Ozawa, J., Kito, N. and Moriyama, H. (2013) Efficacy of strengthening or aerobic exercise on pain relief in peopl with knee osteoarthritis: a systematic review and meta-analysis of randomised controlled trials. Clinical rehabalitation. 27(12).pp.1059-1071.
Zhang, Y. and Jordan, J.M.(2010) Epidemiology of osteoarthritis. Clinics in Geriatric Medicine. 26(3) pp. 355-369.